Having trouble piecing together the clues for the medicine bottle puzzle in Alone in the Dark? Don’t worry; you probably aren’t the only one, as it can be a little confusing from the clues they give. Thankfully, we have removed all the confusion to give you the solution to this puzzle so that you can continue your journey to solving the mystery behind the mansion.

Alone in the Dark Medicine Bottle Puzzle Guide

A few hours into your search for Jeremy, you’ll be tasked with finding some missing medicine bottles. Their locations aren’t kept much of a secret, as the clues will point out which room they’re in, so follow those, get the medicine, and eventually, you’ll find yourself in Lottie’s room with a locked box and a medicine tray lying around. To open the box, you need the combination, and to get the combination, you need to arrange the medicine bottles in the correct order and have them rotated the right way.

The clue given is a stain on each bottle that connects somehow. It sounds easy and should be, but stains can align and connect differently depending on how you look at it. Either way, here’s the solution with the order and rotation of the medicine bottles.

Here’s the code for opening the lock on the box in the room based on the solution above.

Assuming these numbers aren’t randomized and different for each character, this should get you inside the box so that you can continue with the main story. Otherwise, just set the medicine in the order above and look at the bottle numbers. There are three of them: open up the key cipher and match the number with the symbols, which will get you inside the box.

That’s it; you should now be able to continue with the story!